Brain Energy Metabolism in Alzheimer's Disease – Part C, Volume 188

Editor: Subashchandrabose Chinnathambi

ISBN: 9780443345258

Published: August 2026

Format: Softcover

Language: English

Publisher: Elsevier (International Review of Neurobiology, Volume 188)

Description

Brain Energy Metabolism in Alzheimer's Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer's disease and related disorders.

Key Features

Presents current advances in brain energy metabolism and neurodegenerative disease research, with contributions from leading experts in neuroscience, neurobiology, and metabolic research. Covers molecular, cellular, and systemic aspects of metabolic dysfunction in Alzheimer's disease, and explores therapeutic targets, diagnostic approaches, and emerging treatment strategies including nanocarrier-based therapies and HDAC inhibitors.

Coverage

Fifteen chapters examining metabolic therapeutic targets in Alzheimer's disease, brain energy metabolism changes compared with Parkinson's disease, epigenetic modulation via natural compounds, mitochondrial vulnerability and lactate shuttle disruption, astroglial dysregulation in schizophrenia, metabolic disorders and Parkinson's disease, PPAR-γ signalling in ALS and Huntington's disease, cholinesterase-targeting therapeutics, intestinal microbiota in neurodegeneration, nanocarrier-based therapeutic breakthroughs, HDAC inhibitors, the tau-mitochondria connection, brain lipid dysregulation, and mechanisms, markers and therapeutic prospects in metabolic dysregulation.

About the Editor

Subashchandrabose Chinnathambi is Additional Professor at the Department of Neurochemistry, National Institute of Mental Health and Neurosciences Hospital Bangalore, Karnataka, India. His scientific interests include physiopathology of neurodegenerative disorders, Tau cytoskeleton, Tau-GPCR, purinergic and chemokine receptors, Tau stem cells, animal models, neuropharmacology, and therapeutic approaches targeting Tau oligomers and biomarkers for neurodegeneration. He has more than 16 years of research experience in neuroscience and Tau-related research in Alzheimer's disease.

Table of Contents

1. Metabolic Therapeutic Targets in Alzheimer's Disease (AD)
2. Brain Energy Metabolism Changes and Neuropsychological Impairment in Parkinson Disease vs Alzheimer's Disease
3. Modulation of Epigenetic Effect in Alzheimer's Disease via Natural Compounds
4. Energetic Crisis, Mitochondrial Vulnerability and Disruption of Lactate Shuttle in Alzheimer's Disease
5. Astroglial Dysregulation and Gliotransmitter Imbalance in Schizophrenia
6. Metabolic Disorders and Parkinson's Disease
7. Molecular Insights of PPAR-γ Signalling in Amyotrophic Lateral Sclerosis and Huntington's Disease
8. A Comprehensive Review on Therapeutics and Diagnostic Agents Targeting Acetyl and Butyryl Cholinesterases for AD
9. Intestinal Microbiota in Neurodegeneration and Ageing
10. Brain Energy Crisis in Alzheimer's and Parkinson's Disease: Can Nanocarriers Offer a Therapeutic Breakthrough?
11. The Potential of HDAC Inhibitors for Alzheimer's Disease
12. The Tau–Mitochondria Connection and Its Impact on Cellular Energy Metabolism in Alzheimer's Disease
13. Brain Lipid Dysregulation as a Driver of Energy Metabolism Failure in Alzheimer's Disease
14. Metabolic Dysregulation in Alzheimer's Disease: Mechanisms, Markers, and Therapeutic Prospects

Why buy this book?

Part of the established International Review of Neurobiology series, this volume gives researchers and clinicians a single, current reference on the metabolic dimension of Alzheimer's disease, tracing mitochondrial dysfunction, tau-metabolism links, and emerging nanocarrier and HDAC-inhibitor therapies alongside comparisons with Parkinson's disease and ALS. It's a strong addition to neuroscience and neurodegeneration research collections.

Keywords

Brain energy metabolism, Alzheimer's disease, neurodegenerative disease, mitochondrial dysfunction, tau pathology, Parkinson's disease, metabolic therapeutic targets, International Review of Neurobiology

Target Audience

Undergraduates, graduates, academics, and researchers in neurology and neurobiology, academic medical libraries

Genre

Neurodegenerative Disease, Neurology

Q&A

Where can I buy Brain Energy Metabolism in Alzheimer's Disease – Part C?
You can order it directly from CLNZ Books, with worldwide shipping and payment by card, PayPal, or bank transfer.

What is the International Review of Neurobiology series?
It's an established Elsevier book series presenting current research reviews across neuroscience and neurobiology; this is Volume 188, Part C on brain energy metabolism in Alzheimer's disease.

Does this volume compare Alzheimer's with other neurodegenerative diseases?
Yes — chapters compare metabolic changes in Alzheimer's disease with Parkinson's disease, ALS, Huntington's disease and schizophrenia.

Does the volume cover emerging therapies?
Yes, including nanocarrier-based therapeutic approaches and HDAC inhibitors as emerging treatment strategies for Alzheimer's disease.

Who edited this volume?
Subashchandrabose Chinnathambi, Additional Professor at the Department of Neurochemistry, National Institute of Mental Health and Neurosciences Hospital Bangalore, India.

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