Greenberg's Handbook of Neurosurgery, 11th Edition

Mark S. Greenberg, MD (Founding Author) — Nitin Agarwal, MD (Associate Editor, 11th Edition)

ISBN: 9781684207787

Published: October 2026

Format: Paperback

Language: English

Publisher: Thieme

Description

Now in its 11th edition, Greenberg's Handbook of Neurosurgery remains the single most trusted point-of-care reference in neurosurgery, continuously updated since 1990. This new edition spans 24 sections and 118 chapters, covering the full breadth of the specialty from fundamental anatomy and physiology through cranial, spinal, vascular, functional, pediatric, and endovascular neurosurgery. Every chapter has been revised to reflect current national and international clinical guidelines, with more than 6,000 references now housed in the companion digital edition on MedOne, keeping the print volume compact without sacrificing depth.

Key Features

New and expanded coverage of Moyamoya disease, Cushing disease/syndrome, trigeminal neuralgia, adult chronic hydrocephalus, seizure surgery, and intraoperative pathology consultation. Updated spine content including AO Spine injury classifications and metastatic spine tumor management (NOMS framework, Bilsky scale, SORG nomogram). Revised neurovascular and trauma guidance incorporating the 2026 AHA/ASA acute ischemic stroke guidelines, AHA/ASA intracerebral hemorrhage recommendations, the NIH-NINDS TBI classification, and 2023 ACEP mild TBI guidelines. Includes a scratch-off code for complimentary digital access via MedOne, with searchable text and an expanded reference library.

Coverage

Anatomy and physiology; neuro-oncology; cerebrovascular and endovascular neurosurgery; spine and spinal cord surgery; functional and stereotactic neurosurgery; pediatric neurosurgery; neurotrauma and critical care; peripheral nerve surgery; infections of the central nervous system; and perioperative and critical care management.

About the Authors

Mark S. Greenberg, MD, is the founding author of the Handbook of Neurosurgery, a reference first published in 1990 and continuously updated across eleven editions to remain the field's standard point-of-care resource. Nitin Agarwal, MD, joins this edition as Associate Editor, bringing current academic neurosurgical practice and an expanded editorial team of specialist contributors to the revision.

Table of Contents

Section I–III: General Neurosurgery, Neuroanatomy and Physiology, Neurodiagnostics. Section IV–VIII: Neuro-oncology, Cranial Trauma, Cerebrovascular Disease, Endovascular Neurosurgery, Infections. Section IX–XIV: Spine and Spinal Cord Disorders, Peripheral Nerve, Functional and Stereotactic Neurosurgery, Pediatric Neurosurgery. Section XV–XXIV: Critical Care, Pain, Pharmacology, Radiosurgery, and Perioperative Management, concluding with appendices of scales, classifications, and quick-reference tables.

Why buy this book?

For institutions and practitioners who need one dependable, continuously updated neurosurgical reference, the 11th edition of Greenberg's is the current standard. It is the edition residents study for board preparation and the volume attendings keep within reach in clinic and on call. With new 2026 guideline updates already incorporated, this is a timely acquisition for any library serving a neurosurgery, neurology, or neurocritical care program.

Keywords

Greenberg's Handbook of Neurosurgery, neurosurgery reference, neurosurgery handbook 11th edition, Nitin Agarwal, Mark Greenberg neurosurgery, neurosurgical board review, cranial and spinal surgery reference, neuro-oncology, cerebrovascular neurosurgery, AO Spine classification

Target Audience

Neurosurgeons, neurosurgery residents and fellows, academic medical libraries, hospital and teaching hospital libraries, neurology and neurocritical care specialists, physician assistants and nurse practitioners in neurosurgery

Genre

Medicine, Neurosurgery, Clinical Reference, Neuroscience

Q&A

Q: What edition is the current Greenberg's Handbook of Neurosurgery?
A: The 11th edition, published in October 2026 by Thieme, with Mark S. Greenberg as founding author and Nitin Agarwal as associate editor.

Q: Does the 11th edition include updated stroke and trauma guidelines?
A: Yes. It incorporates the 2026 AHA/ASA acute ischemic stroke guidelines, updated intracerebral hemorrhage management, the NIH-NINDS TBI classification, and 2023 ACEP mild TBI guidelines.

Q: Is Greenberg's Handbook of Neurosurgery suitable for board exam preparation?
A: Yes, it is widely used by neurosurgery residents preparing for board examinations due to its comprehensive, concise, point-of-care format.

Q: Does the print edition include digital access?
A: Yes, each print copy includes a scratch-off code for a complimentary digital edition on MedOne, which also hosts the expanded 6,000+ reference library.

Q: What topics were newly added or expanded in this edition?
A: New and expanded content includes Moyamoya disease, Cushing disease/syndrome, trigeminal neuralgia, adult chronic hydrocephalus, seizure surgery, and updated AO Spine and metastatic spine tumor frameworks.

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