McKee's Pathology of the Skin with Clinical Correlations (2 Volume Set)

Calonje, J. (Editor) — Brenn, T. (Editor) — Lazar, A. (Editor) — Billings, S. (Editor)

ISBN: 9780443113482

Published: July 2026

Format: Hardcover

Language: English

Publisher: Elsevier

Description

For trusted, comprehensive, and lavishly illustrated information on dermatopathology, look no further than McKee's Pathology of the Skin, 6th Edition. This fully revised two-volume reference provides clinical guidance from internationally renowned experts along with details on etiology, pathogenesis, histopathology, and differential diagnosis, making it an unparalleled resource for practicing dermatopathologists and general pathologists who sign out skin biopsies.

Key Features

• Combines pathological detail with superb descriptions and illustrations of clinical manifestations, a unique combination not found in comparable references.
• Highly illustrated coverage of inflammatory, neoplastic, and infectious skin diseases, with dedicated sections on clinical correlations, histopathological features, and differential diagnoses.
• More than 5,000 histopathologic and clinical illustrations, with bulleted clinical-feature lists and differential-diagnosis tables for quick reference at the bench.
• Updated coverage of key molecular aspects of disease, including targeted therapy and personalized medicine.
• Extensively revised melanoma chapter reflecting recent advances in cancer research and molecular mechanisms relevant to targeted therapy.
• Expanded discussion of biologics for inflammatory disease, new antigens/antibodies for tumor diagnosis and staging, next-generation sequencing and other molecular assays, and improved clinical-pathological correlations for integrated care.
• Includes eBook access with purchase, allowing full-text search, note-taking, highlighting, and read-aloud functionality.

Coverage

36 chapters spanning the full range of dermatopathology: structure and function of the skin; specialized diagnostic techniques; keratinization disorders; blistering and acantholytic diseases; spongiotic, psoriasiform, lichenoid, and granulomatous dermatoses; connective tissue and vascular disease; infectious and HIV/AIDS-associated skin disease; pigmentation disorders; hair and nail disease; the full spectrum of cutaneous tumors (melanocytic, lymphoproliferative, adnexal, and connective tissue); sentinel lymph node biopsy; and cutaneous metastases.

About the Authors

J. Eduardo Calonje, MD, DipRCPath — Director of Diagnostic Dermatopathology, Department of Dermato-Histopathology, St John's Institute of Dermatology, St Thomas' Hospital, London, UK.

Thomas Brenn, MD, PhD, FRCPath — Professor of Pathology and Laboratory Medicine and Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Alexander J. Lazar, MD, PhD — Associate Professor, Departments of Pathology and Dermatology, Sections of Dermatopathology and Sarcoma Pathology, The University of Texas M.D. Anderson Cancer Center, USA.

Steven D. Billings, MD — Co-Section Head, Department of Anatomic Pathology, Cleveland Clinic Main Campus, USA.

Table of Contents

1. The structure and function of skin. 2. Specialized techniques in dermatopathology. 3. Disorders of keratinization. 4. Inherited and autoimmune subepidermal blistering diseases. 5. Acantholytic disorders. 6. Spongiotic, psoriasiform and pustular dermatoses. 7. Lichenoid and interface dermatitis. 8. Superficial and deep perivascular inflammatory dermatoses. 9. Granulomatous, necrobiotic and perforating dermatoses. 10. Inflammatory diseases of the subcutaneous fat. 11. Histopathology of factitious skin lesions. 12. Diseases of the oral mucosa. 13. Diseases of the anogenital skin. 14. Degenerative and metabolic diseases. 15. Cutaneous adverse reactions to drugs. 16. Neutrophilic and eosinophilic dermatoses. 17. Vascular diseases. 18. Idiopathic connective tissue disorders. 19. Infectious diseases of the skin. 20. HIV/AIDS-associated cutaneous diseases. 21. Disorders of pigmentation. 22. Diseases of collagen and elastic tissue. 23. Diseases of the hair. 24. Diseases of the nails. 25. Tumors of the surface epithelium. 26. Melanocytic nevi and melanoma. 27. Tumors of the conjunctiva. 28. Sentinel lymph node biopsies. 29. Cutaneous lymphoproliferative diseases and related disorders. 30. Cutaneous metastases and Paget's disease of the skin. 31. Tumors of the hair follicle. 32. Tumors and related lesions of the sebaceous glands. 33. Tumors of the sweat glands. 34. Cutaneous cysts. 35. Connective tissue tumors. 36. Animal models of skin disease.

Why buy this book?

McKee's is the benchmark dermatopathology reference worldwide — the one combination of rigorous histopathology and genuine clinical correlation that lets a pathologist sign out a difficult skin biopsy with confidence. This 6th Edition brings the molecular and targeted-therapy content fully up to date, and the included eBook means the full searchable text travels with you between the bench and the clinic.

Keywords

dermatopathology, skin pathology, McKee, Calonje, skin biopsy, melanoma pathology, differential diagnosis skin, histopathology atlas, surgical pathology, dermatology reference

Target Audience

Dermatopathologists, general and surgical pathologists, dermatologists, pathology residents and fellows, academic medical libraries

Genre

Dermatology, Dermatopathology, Medical Reference, Surgical Pathology

Q&A

Q: What does the 6th edition of McKee's Pathology of the Skin add compared to the 5th edition?
A: The 6th Edition brings a fully revised melanoma chapter, updated coverage of biologics and targeted therapy, new antigens/antibodies for tumor diagnosis and staging, and next-generation sequencing content reflecting current molecular practice.

Q: Is McKee's Pathology of the Skin suitable for general pathologists, or only dermatopathology specialists?
A: Both. It's written as a must-have reference for practicing dermatopathologists and for general pathologists who sign out skin biopsies as part of a broader caseload.

Q: Does the print edition of McKee's Pathology of the Skin include digital access?
A: Yes — an eBook version is included with purchase, with full-text search, note-taking, highlighting, and read-aloud functionality.

Q: How is the content organized across the two volumes?
A: Across 36 chapters covering inflammatory, infectious, pigmentary, and neoplastic skin disease, each with histopathological features, clinical correlations, and differential diagnosis tables.

Q: Where can I buy McKee's Pathology of the Skin with Clinical Correlations (2 Volume Set), 6th Edition?
A: Directly from CLNZ Books, with worldwide shipping and secure payment by card or PayPal.

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